🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧬 Genetic Analysis

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📊 Resource Allocation by Research Phase:

📚 Data Analysis

🧪 Experimental Design

🔬 Clinical Trials

💊 Treatment Development

Trial Search

Current Search Criteria:

Intervention: Full-course chemoradiotherapy

Found 9 matching trials

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

PHASE2

Preoperative radiotherapy combined with 5-fluorouracil/capecitabine is curr...

Status

Unknown

Location

Envafolimab

Start Date

2023-04-01

Trial ID

NCT06239870

Treatments Being Tested

Envafolimab combined with chemoradiotherapy in the whole course of neoadjuvant therapy

Under Whole-course of Immunotherapy, Gradient Fractionated RT with CCT Versus CFRT with CCT for LANPC Who Achieved PR Post Induction Chemotherapy.

PHASE3

This prospective trial aims to enroll patients with stage III-IVA (AJCC 8th...

Status

Recruiting

Location

The Fifth Affiliated Hospital of Sun Yat-sen University

Start Date

2024-07-30

Trial ID

NCT06675214

Treatments Being Tested

Full course of PD-1/PD-L1 blockades Cisplatin-based induction chemotherapy Standard-dose IMRT Gradient Fractionated IMRT Concurrent Chemotherapy

Radiotherapy Dose Escalation for Non-operative Management of Unresectable Locally Recurrent Rectal Cancer (STEP-UP)

The optimal curative-intent management of locally recurrent rectal cancer (...

Status

Recruiting

Location

Radiotherapiegroep

Start Date

2026-09-01

Trial ID

NCT07721181

Treatments Being Tested

SBRT Hyperfractionated chemo-reirradiation Full-course chemoradiotherapy

Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer

PHASE3

NEEDS is a pragmatic open-label, randomised, controlled, phase III, multice...

Status

Recruiting

Location

McGill University Health Centre

Start Date

2020-11-27

Trial ID

NCT04460352

Treatments Being Tested

Neoadjuvant radiotherapy (arm A)Carboplatin, paclitaxel Esophagectomy Neoadjuvant radiotherapy (arm B)Carboplatin, paclitaxel Cisplatin, paclitaxel Oxaliplatin, calcium folinate, 5-fluorouracil Esophagectomy

Preoperative Radiotherapy and Local Excision in Rectal Cancer

PHASE3

According to the current opinion, local excision in rectal cancer should be...

Status

Unknown

Location

M. Sklodowska-Curie Memorial Cancer Centre

Start Date

2003-11

Trial ID

NCT00738790

Treatments Being Tested

Short course of radiotherapy Radiochemotherapy

Induction Chemotherapy for Locally Recurrent Rectal Cancer

PHASE3

This is a multicentre, open-label, parallel arms, phase IIII study that ran...

Status

Recruiting

Location

UZ Gent

Start Date

2020-11-13

Trial ID

NCT04389086

Treatments Being Tested

Combination drug Chemoradiotherapy Surgery locally recurrent rectal cancer

Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy

PHASE3

This prospective trial aims to enroll patients with high-risk stage III-IVA...

Status

Recruiting

Location

Sun Yat-sen University Cancer Center

Start Date

2023-10-09

Trial ID

NCT06092957

Treatments Being Tested

Cisplatin-based induction chemotherapy Full course of PD-1/PD-L1 blockades Reduced-dose IMRT Standard-dose IMRT Concurrent Chemotherapy

A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue

PHASE2

This clinical study investigates the anti-inflammatory and anti-cancer prop...

Status

Not Yet Recruiting

Location

Linkou Chang Gung Memorial Hospital

Start Date

2026-01-01

Trial ID

NCT07248020

Treatments Being Tested

Curcumin (BCM-95®)

Reduced-dose Versus Conventional-dose Intensity-modulated Radiation Therapy for Locally Advanced Nasopharyngeal Carcinoma With Remission After Induction Chemotherapy and Immunotherapy

PHASE3

To explore the efficacy and safety of reduced-dose radiotherapy combined wi...

Status

Recruiting

Location

The Fifth Affiliated Hospital of Guangzhou Medical University

Start Date

2025-11-18

Trial ID

NCT07328841

Treatments Being Tested

Full course of PD-1blockades Cisplatin-based induction chemotherapy Standard-dose radiotherapy Reduced-dose radiotherapy Concurrent Chemotherapy

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